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Open access Oct 2026

Predictive value of life’s crucial 9 for all-cause mortality and cardiovascular disease: an analysis of the PURE-China cohort study

Cardiovascular health (CVH) metrics have progressed from Life’s Simple 7 to Life’s Essential 8 (LE8). Life’s Crucial 9 (LC9) extends LE8 by incorporating mental health, yet whether LC9 offers incremental prognostic value for mortality and cardiovascular disease (CVD) remains unclear, particularly in Chinese popul...

J. Hao, Z. Liu, B. Hu et al. · 0 citations
Open access Oct 2026

Plasma proteomic signatures of subclinical atherosclerosis progression for cardiovascular risk stratification: A cohort study

Background Existing risk stratification tools inadequately identify individuals with subclinical atherosclerosis (SA) who could benefit from early intervention. This study aimed to develop protein risk scores (ProtRSs) for SA progression and assess their incremental value for atherosclerotic cardiovascular disease (ASC...

Y. Huang, Rui Gao, J. Li et al. · 0 citations

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