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Review Open access Sep 2026

Current Landscape of RAS-Targeted Therapy for Pancreatic Cancer.

Pancreatic ductal adenocarcinoma (PDAC) continues to carry a poor prognosis, and only incremental gains in systemic therapy have been made over the past decade. Because activating KRAS mutations are present in more than 90% of PDAC and serve as the inciting oncogenic driver, RAS has long been a coveted but elusive ther...

Y. L. Wu, B. Herzberg, G. Manji · 0 citations

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