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Sep 2026

Abstract A050: NEIL2 regulates RNA polymerase II dynamics to suppress transcription–replication conflicts in pancreatic cancer

Transcription–replication conflicts (TRCs), arising from spatiotemporal interference between transcription and replication machinery, are major sources of genome instability in cell. In pancreatic ductal adenocarcinoma (PDAC), oncogenic KRAS promotes TRC formation, and pharmacological exacerbation of endogenous T...

Fan Meng, Tony Fernandez, C. Luan et al. · 0 citations
Review Open access Sep 2026

Cardiovascular Risk Triage Schema for Patients With Prostate Cancer Treated With Hormone Therapy.

IMPORTANCE Cardiovascular disease (CVD) is a leading noncancer cause of death among patients with prostate cancer (PC). Population-based risk calculators do not account for treatment-related effects of androgen-deprivation therapy (ADT) and androgen receptor pathway inhibitors (ARPis), and they have not been validated...

A. Guha, Ana Barac, M. Ryan et al. · 0 citations

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