In continuous analyses, only AES and depression severity were significantly associated with CMD incidence, though effect sizes were comparable across symptom profiles, suggesting a general rather than symptom-specific depression burden on cardiometabolic health risk.
J. Zwiep, Y. Milaneschi, C. Vinkers et al.· Journal of Affective Disorde...· 0 citations
OBJECTIVE
Major depressive disorder (MDD) is biologically heterogeneous and encompasses diverse symptom presentations. The authors used large-scale plasma proteomics to examine proteomic associations with categorical MDD status, continuous depression symptom severity, and DSM-IV-defined melancholic and atypical symptom...
K. Watson, Mariska Bot, I. Kosti et al.· American Journal of Psychiat...· 0 citations
This study provides hierarchical insights into the cross-sectional and longitudinal implications of health, stress, and lifestyle exposures for the plasma metabolome in the Netherlands Study of Depression and Anxiety.
D. Klose, Y. Milaneschi, Laura K. M. Han et al.· EBioMedicine· 0 citations
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