Surgical repair of gastroesophageal (GE) defects is a formidable clinical challenge, plagued by high leakage, fistula recurrence and life-threatening complications due to gastric acid exposure and persistent mechanical stress. To address this unmet need, we developed a robust bio-supportive (RBS) hydrogel patch for imm...
Xing-Qi Song, Zhe-Wei Shuai, Wei-Yan Sun et al.· Advancement of science· 0 citations
CDH3 is defined as a biomarker and therapeutic target linking malignant epithelial plasticity to immunosuppressive niche formation and adverse clinical behavior in TETs.
Yuntao Feng, Jing-Yu Chen, Lang Xia et al.· Advancement of science· 0 citations
CarHE (contrastive alignment of gene expression for hematoxylin and eosin images), a multimodal pretraining framework that infers high-dimensional spatial transcriptomic profiles from routine H&E-stained slides, provides a cost-effective and scalable framework for H&E-based spatial inference, supporting further validat...
Jiawei Zou, Kai Xiao, Ze-Xi Chen et al.· Cancer Research· 0 citations
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