Skip to content

Author

Y. Soignier

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Jul 2026

Leveraging modular TriKE-PACC molecules capable of dual-antigen targeting to enhance NK-cell immunotherapy in AML 2257266

The engineered TriKEs with Poly Antigen Cytokine Complexes (TriKE-PACCs), which combine dual AML-specific targeting with NK activation and persistence, enhance NK cell proliferation and antitumor activity compared to TriKEs or IL-15 therapies alone.

Anders W. Matson, Caden Caligiuri, Katherine M. Koehler et al. · 0 citations
Jul 2026

Abstract A021: Enhancing NK cell immunotherapy in non-small cell lung cancer using dual-antigen targeting Tri-Specific Killer Engagers (TriKEs/TriKE PACCs)

Treatment with TriKE-PACCs significantly enhanced NK cell degranulation, cytokine production, and tumor killing compared to single-antigen TriKEs and IL-15 alone, particularly in heterogeneous antigen settings.

Rachel N. Steinmetz, S. Phung, Joshua T. Walker et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.