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Open access Sep 2026

Association of statin use and left ventricular function in patients with breast cancer receiving trastuzumab

Aims We examined the association between statin use and changes in left ventricular ejection fraction (LVEF) during trastuzumab therapy in women with breast cancer. Methods: This post-hoc analysis of the CHECK HEART-BC study included 215 patients with normal baseline LVEF and 12-month echocardiographic follow-up. We as...

K. Nochioka, Y. Terui, Aika Udagawa et al. · 0 citations

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