Open access
Sep 2026
Quinine modulates PD-L1 and STAT3 in MCF-7 cells: An in silico and in vitro study
Findings indicate that quinine suppresses MCF-7 cell growth and migration by downregulating PD-L1 and STAT3 gene expression, reducing VEGF levels, and increasing TINAGL-1 levels, highlighting the compound’s potential for PD-L1 inhibition in cancer.
Fuat Karakuş, Sedat Köstekci, B. Kuzu et al.
· International Journal of Sec... · 1 citation