Author

Y. Zhuo

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Open access Aug 2026

CD38-activated macrophages drive age-related placental senescence by depleting NAD+ in decidual stromal cells

As delayed childbearing becomes increasingly common, elucidating the mechanisms of age-related placental senescence is critical for the development of effective therapeutic strategies. Here, we integrate metabolomics, single-cell RNA sequencing, and spatial transcriptomics to uncover conserved features of aged placenta...

Lun Hua, Xiao-Han Yang, Deng-Feng Gao et al. · Nature Communications · 0 citations

Open access Aug 2026

Fermented Liquid Feeding Modulates Intramuscular Fat Deposition and Lipid Composition in Pork: Integrated Metabolomic and Proteomic Insights

Fermented liquid feeding (FLF) has been proposed as a nutritional intervention with the potential to influence pork quality, yet its effects on intramuscular fat deposition and muscle lipid composition remain unclear. In this study, pigs were fed a basal dry feed, liquid feed, or FLF regimen for 173 days, and porcine m...

L. Wang, Hefeng Luo, Zhongyang Guo et al. · Foods · 0 citations

Open access Aug 2026

Taurolithocholic acid alleviates hepatic glycolipid dysregulation in low-birth-weight piglets by activating HNF4α and FXR

In vivo studies indicated that exogenous supplementation of TLCA significantly ameliorated hepatic glycolipid metabolism and improved overall liver function in LBW neonatal piglets, providing potential nutritional strategies to improve liver health in LBW piglets and a theoretical basis for using BAs as feed additives...

Tianle Gao, Hairong Liang, Meizheng Li et al. · Journal of Animal Science an... · 0 citations