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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Ya-Jie Lu

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2 papers indexed here

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Open access Sep 2026

Genetically predicted sleep duration in relation to the risk of breast tumors

Aim To investigate the causal relationship between genetically predicted sleep duration and breast tumors using a bidirectional two-sample Mendelian randomization (MR) analysis. Methods A bidirectional two-sample MR analysis was performed using genome-wide association study (GWAS) summary statistics. The inverse varia...

Li-Tong Shao, Dan Zhao, Jing Ji et al. · 0 citations
Aug 2026

Tumor-derived KLK5 activates TMEM158+ cancer-associated fibroblasts to induce CD8+ T cell exhaustion and confer immunotherapy resistance in lung cancer.

AIM Immune checkpoint blockade (ICB) has improved the treatment landscape of lung squamous cell carcinoma (LUSC), but durable clinical benefit is limited by frequent therapeutic resistance. We aimed to define the microenvironmental mechanisms underlying ICB resistance in LUSC. METHODS Surgical specimens from LUSC pat...

Shuangpeng Pu, Guo-Dong Li, Yu-Ran Jiang et al. · 0 citations

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