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Open access Aug 2026

Shared Treg dysregulation underlies psoriasis vulgaris and atopic dermatitis through the PHF19-PRC2 epigenetic axis

Background Psoriasis vulgaris (PV) and atopic dermatitis (AD) are chronic inflammatory skin diseases characterized by distinct dominant T cell subsets, yet emerging evidence suggests overlapping immune mechanisms. Whether a shared Treg abnormality underlies both diseases remains unclear. Methods Single-cell RNA sequenc...

Yi-Ting Lin, Xiao-Lei Su, Ming-Zhu Jin et al. · 0 citations

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