Oct 2026
Dihydrotanshinone I suppresses ovarian cancer by targeting splicing factor SRSF1 to regulate the long non-coding RNA SLC8A1-AS1/FOXO1 axis.
BACKGROUND Ovarian cancer (OC) is a lethal malignancy with limited therapies. The natural compound dihydrotanshinone I (DHT) exhibits broad antitumor activity, yet its precise molecular targets and mechanistic interplay with oncogenic lncRNAs in OC remain largely unexplored. PURPOSE This study aimed to investigate th...
Xin-Ming Tu, Rui-Wen Yang, Cheng-Yu Miao et al.
· Phytomedicine · 0 citations