Aug 2026
TRDMT1-dependent m5C modification of TLR4 mediates the protective effects of Shaoyao decoction in TNBS-induced Crohn's disease.
SYD can alleviate intestinal inflammation, inhibit apoptosis, and protect the intestinal barrier in the CD model, and mechanistic studies indicated that TRDMT1 and TLR4 were involved in the protective effects of SYD against CD-like colitis.
Yonghao Deng, Jing Wang, Meng-Yi Li et al.
· International Immunopharmaco... · 0 citations