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Author

Ya-Lan Yang

2 papers indexed here

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Review Open access Oct 2026

Impact of Aggregation on the Immunogenicity of Therapeutic Recombinant Biological Products

Background: Therapeutic recombinant biological products are essential in modern medicine, but their immunogenicity remains a major concern for both clinical safety and therapeutic efficacy. Protein aggregation may occur during manufacturing, storage, transportation, and administration, potentially increasing immune rec...

Xiao-Ying Chen, Sha Guo, Xiao-Rui Feng et al. · 0 citations
Open access Sep 2026

Critical Quality Attribute Investigation and Analytical Method Establishment for Glyco-Site-Specific Anti-HER2 Bispecific ADC

An analytical method suite was developed for the bispecific ADC to comprehensively characterize and appropriately control its critical quality attributes, thereby guiding the research, development, and manufacturing process optimization of the ADC product and ensuring its safety, efficacy, and quality consistency.

Xiao-Juan Yu, Le-Le Wang, Wei-Rong Cao et al. · 0 citations

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