Author

Ya-Li Xu

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Open access Aug 2026

Transglutaminase 2 regulates vimentin-dependent proteostasis during macrophage activation

A TG2–vimentin axis that controls macrophage activation through proteostasis regulation, linking cytoskeletal remodeling to inflammatory signaling is defined.

Ya-Li Xu, Ting Su, Hricha Mishra et al. · Science Advances · 0 citations

Open access Jul 2026

PhiKan 083 Inhibits MYCN Expression in Liver Cancer Cells Independent of p53 Pathways.

Findings suggest that PK83 suppresses MYCN expression and preferentially affects MYCN-high HCC cells in a p53-independent manner, warranting further preclinical investigation of PK83 and related compounds in MYCN-associated cancers.

Ya-Li Xu, Hricha Mishra, Masataka Takahashi et al. · ACS Pharmacology & Translati... · 0 citations