Open access
Aug 2026
Enhanced heparosan biosynthesis in Corynebacterium glutamicum by systematic metabolic engineering and translation-level fine-tuning
This study systematically engineered Corynebacterium glutamicum, a Generally Recognized as Safe (GRAS) microorganism, to synthesize heparosan via two complementary strategies, which provide valuable references for constructing high-efficiency cell factories for other complex compounds.
Jie Zhang, Ya-Nan Cui, Pei-Yi Zhang et al.
· Bioresources and Bioprocessi... · 0 citations