The identification of SiTRAF suggests the presence of a functional MyD88-TRAF signaling axis in the sea urchin Strongylocentrotus intermedius.
Tumor necrosis factor receptor-associated factors (TRAFs) are key signaling proteins involved in cellular innate immune pathways. However, knowledge of TRAF genes in echinoderms remains limited. We cloned a novel TRAF gene (SiTRAF) from the sea urchin Strongylocentrotus intermedius. The full-length open reading frame o...