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Author

Ya-Tian Cheng

2 papers indexed here

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Aug 2026

Rutin targeting NOX4 alleviates sepsis-induced acute lung injury via inhibition of NET formation through the ROS/MAPK/PAD4 pathway.

Neutrophil extracellular traps (NETs) have been identified as pivotal contributors in driving excessive inflammation and organ damage during sepsis. Rutin has shown broad therapeutic potentials in inflammatory, infection, and cancer disease models. However, its role in sepsis-associated acute lung injury (ALI) has not...

Yanhui Zhu, Mengdi Shao, Qingyan Zheng et al. · 0 citations
Aug 2026

11-O-galloylbergenin alleviates LPS-stimulated inflammation in RAW 264.7 macrophages by targeting Grb2, RhoA, and Cdc42 in the RAS signaling pathway.

OBJECTIVE This study aimed to explore the anti-inflammatory mechanism of 11-O-galloylbergenin in macrophages. METHODS Lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages were treated with 11-O-galloylbergenin. Cytotoxicity was assessed by 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay,...

Kun You, Lang Qin, Si-Man Yang et al. · 0 citations

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