Stroke ranks among the leading global causes of mortality and permanent disability. Its secondary brain injury arises from multiple interrelated pathological cascades, including oxidative stress, neuroinflammation, disrupted autophagy-apoptosis balance, excitotoxicity, iron dyshomeostasis, and blood–brain barrier (BBB)...
Yi-Fan Yuan, Cui-Mei Xie, Ya-Ting Huang et al.· Frontiers in Pharmacology· 0 citations
Physical inactivity and mechanical unloading induce skeletal muscle atrophy and are associated with systemic metabolic disorders, but the molecular basis linking muscle disuse to liver injury remains unclear. Human cohort analyses (CHARLS, NHANES), a mouse hindlimb immobilization model, and multi-level in vitro systems...
Xiu-Ru Li, Jingling Peng, Ya-Ting Huang et al.· Biochimica et Biophysica Act...· 0 citations
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