Author

Ya Wang

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Open access Oct 2026

Using the housekeeping gene cpn60 as a marker for microbial community profiling and viability assessment

High-throughput sequencing has revolutionized microbiome research, yet distinguishing viable from nonviable microbes in complex communities remains challenging. Microbial viability underlines microbiome function, which is mostly driven by living, active members. Transcriptional activity of genes has been suggested...

Ya Wang, Kelsey N. Thompson, Sagun Maharjan et al. · Microbiome · 0 citations

Open access Sep 2026

Microbial transmission and ecology of human and environmental microbial communities in childcare centers

Abstract Background Early-life microbial exposures profoundly impact lifelong health trajectories by shaping immune maturation and modulating disease risk, e.g. as described by the "hygiene hypothesis." Childcare facilities represent a critical yet understudied source of microbial exposures where preschool-aged childre...

Di Chen, Ya Wang, Daniel M. Portik et al. · Research Square · 0 citations

Open access Aug 2026

Complete genome-derived metabolic interactions reveal the impact of gut ecology on human health.

This work leverage 1,150 complete genomes to construct genome-scale metabolic models, demonstrating that draft assemblies introduce systematic artifacts and omit critical transport functions, and connects genome completeness with microbial ecological organization and provides a framework for linking metabolic interacti...

Yu-He Gu, Haoyu Wang, Jin-Long Yang et al. · Cell Reports · 0 citations