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Author

Ya Wen

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Oct 2026

A Mitochondria-Modulating Nanosystem for Rheumatoid Arthritis Immunotherapy via Inflammatory Cascade Disruption.

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation within joints, where macrophage-driven inflammatory cascade caused by mitochondrial dysfunction significantly contributes to the pathogenesis. Through recruitment and activation of neutrophils from circulation, these macrop...

Qing-Shui Wen, Yi Jin, Ying Zhou et al. · 0 citations
Oct 2026

Mitochondria-Nanozyme Hybrid Therapeutic for Modulation of the Inflammatory Cascade in Psoriasis.

The chronic recurrence of psoriasis is driven by a self-amplifying inflammatory cascade in which oxidative stress and mitochondrial metabolic dysfunction reinforce each other, and single-target conventional therapies often fail to break this cycle. Here, we present a micro-nano hybrid system, Mito-Ce, constructed by co...

Si-Yu Chen, Ya-Nan Wei, Wei Huang et al. · 0 citations

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