Ya-Wen Guo

Therapy-induced senescent cancer-associated fibroblasts in cervical cancer: Mechanisms of treatment resistance and therapeutic opportunities

Cervical cancer remains a major global health burden, and concurrent chemoradiotherapy (CCRT) is the standard treatment for locally advanced disease. However, a substantial proportion of patients develop residual disease, recurrence, or progression after treatment. In addition to tumor cell–intrinsic mechanisms,...