Review
Open access
Aug 2026
Self-Resistance as a Functional Beacon: Target-Directed Microbial Genome Mining from Classical Discovery to Automated Pipelines
This review summarizes the biological basis, workflow, representative advances, and limitations of self-resistance-gene guided discovery as a target-directed genome mining framework supported by tools and databases including ARTS, FunARTS, antiSMASH, and MIBiG.
Jiaxin Wu, Meng-Xue Qiao, Ya-Yue Ma et al.
· Microorganisms · 0 citations