Review
Open access
Jul 2026
Dual-module aCAR-iCAR NK cells for solid tumors: cascade resistance mechanisms, AI-driven engineering, and precision stratification
A balanced, evidence-graded theoretical framework for next-generation CAR-NK development against solid tumors is provided, and testable hypotheses for future mechanistic and clinical investigations are generated.
Chenru Ma, Yafei Zhuang, Song-Chen Han et al.
· Frontiers in Immunology · 0 citations