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Author

Ya-Fen Wang

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Jul 2026

GNAS drives gastric cancer progression via pyrimidine metabolic reprogramming and immune-microenvironment remodeling

This work identified GNAS as a key metabolic hub gene, which is consistently upregulated in highly malignant subsets and strongly predictive of poor patient survival, and Targeting the GNAS-mediated metabolic-transcriptional axis exposes a novel therapeutic vulnerability.

Xin-Yi Wang, Heng Tian, Jiaju Wang et al. · 0 citations

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