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Author

Yaiza Senent

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Oct 2026

Epigenetic Priming Sensitizes Metastatic Breast Cancer to Checkpoint Blockade by Rewiring the Tumor-Immune Microenvironment.

Immune checkpoint blockade (ICB) has shown limited efficacy in metastatic breast cancer. Resistance mechanisms involve suppressive myeloid and stromal populations in the tumor microenvironment (TME). In this issue of Cancer Research, Gonzalez and colleagues integrate single-cell transcriptomics, spatial proteomics, fun...

Yaiza Senent, R. Manguso · 0 citations

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