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Author

Yajun Duan

2 papers indexed here

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Open access Aug 2026

Hepatic ChREBP Drives Cardiac Remodeling via ApoM Non-transcriptional Repression

BACKGROUND: Pathological cardiac remodeling is a hallmark of numerous cardiovascular diseases and develops into heart failure. As a systemic disease, effective treatments for cardiac remodeling from a tissue crosstalk perspective are still significantly unmet. METHODS: Hepatocyte-specific ChREBP (carbohydrate response...

Shuang Zhang, Zhen-zhen Zhang, Zi-Han Ma et al. · 0 citations
Open access Jul 2026

ACSS2-KAT5 complex-driven histone crotonylation orchestrates a pro-inflammatory program to promote the transition from MASLD to MASH

Inflammation is a pivotal driver of the progression from metabolic dysfunction-associated steatotic liver disease (MASLD) to metabolic dysfunction-associated steatohepatitis (MASH), an aggressive form associated with substantial liver-related mortality. However, the molecular mechanisms underlying the initiation and pe...

Xiao Wen, Ke Wu, Mengyao Wang et al. · 0 citations

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