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Author

Yan-Bao Yu

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Open access Aug 2026

Perilipin 2 drives cisplatin-induced acute kidney injury in young but not aged kidneys

Cisplatin is a widely used chemotherapeutic agent, but acute kidney injury (AKI) remains its dose-limiting toxicity, particularly in older patients. In recent years, dysregulated lipid metabolism has emerged as a key driver of cisplatin nephrotoxicity; however, the underlying mechanisms and their modulation across ages...

Saiya Zhu, Chen Dai, Kelly Zheng et al. · 0 citations

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