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Open access Sep 2026

CircHIPK3 promotes the progression of B-cell acute lymphoblastic leukemia in children by binding to STAT3

Circular RNAs (circRNAs) have emerged as critical post-transcriptional regulators in hematological malignancies; however, the specific role and molecular mechanism of circHIPK3 in pediatric B-cell acute lymphoblastic leukemia (B-ALL) remain unexplored. circHIPK3 expression was profiled in clinical B-ALL sp...

Yu Zheng, Yun-Peng Li, Xiu-Li Zhu et al. · 0 citations
Open access 2026

METTL16 promotes PD-L1 expression and mediates immunosuppression in B-cell lymphomas via m6A methylation.

OBJECTIVES Immune Checkpoint Inhibitors (ICIs) have changed cancer treatment. Altered expression of methyltransferase-like 16 (METTL16), one of the initial m6A "writers", is associated with malignant progression. METTL16 is a methyltransferase that may influence the treatment response of B-cell lymphoma (BCL). METHOD...

Yan Chen, Sen Cao, Xiaofei Lu et al. · 0 citations

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