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Author

Yan-Feng Li

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Open access Oct 2026

Machine learning and multi-omics analyses reveal CLDN1 as a candidate marker associated with colorectal cancer invasion and nutlin-3a (-) response.

OBJECTIVE Colorectal cancer (CRC) is molecularly, cellularly and spatially heterogeneous, and current staging systems and biomarkers incompletely explain prognosis and treatment response. This study integrated transcriptomics, machine learning, single-cell RNA sequencing, spatial transcriptomics and in vitro experiment...

Wenqi Shan, Qian-Yu Li, Wei Yuan et al. · 0 citations

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