Sep 2026
Porcine TRIM45 negatively regulates the RLR signaling pathway by targeting IKKε for protein degradation.
The tripartite motif 45 (TRIM45) protein belongs to the RING-type E3 ubiquitin ligases and exerts multiple biological functions in cell signaling and inflammation regulation by catalyzing ubiquitination of adaptor proteins in the corresponding cascades. In the present work, we obtained the porcine TRIM45 (porTRIM45) co...
Chen-Xi Li, Jing-Jing Li, Shi-Yu Wang et al.
· Developmental and Comparativ... · 0 citations