Author

Yan-Hui He

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Open access Sep 2026

Activation of alpha-2 adrenoceptors in locus coeruleus alleviates prenatal lipopolysaccharide-induced cognitive deficits in the offspring of rats

The locus coeruleus (LC), the brain’s principal source of norepinephrine, critically regulates cognitive function. While our previous work established that prenatal lipopolysaccharide (LPS) exposure causes cognitive deficits in rat offspring, the underlying mechanisms and potential therapeutic targets remained unknow...

Xue-Qin Hao, Yi-Fan Fu, Chong-Wei Yang et al. · Molecular Brain · 0 citations

Review Open access Sep 2026

Neuroplastic mechanisms of chronic pain: Implications and future directions

Chronic pain is now increasingly viewed as aberrant neuroplasticity rather than a protracted expression of peripheral nociception. This review integrates current knowledge through the lens of a peripheral-to-central paradigm, whereby peripheral sensory sensitization contributes to pain initiation, spinal excitation–inh...

Kai-Kai Wang, Yan-Hui He, Jin-Hai Liu et al. · Perioperative Precision Medi... · 0 citations