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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Yan-Jun Zhou

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2 papers indexed here

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Aug 2026

Targeting GEM Reprograms Macrophages and Overcomes Immunotherapy Resistance in Esophageal Squamous Cell Carcinoma.

Esophageal squamous cell carcinoma (ESCC) exhibits heterogeneous responses to immune checkpoint blockade, highlighting the need to define tumor-intrinsic mechanisms driving resistance to PD-L1 inhibition. Here, we identified GTP-binding protein overexpressed in skeletal muscle (GEM) as a tumor cell-intrinsic regulator...

Lin-Feng Wu, C. Ren, Yi-Fei Zhang et al. · 0 citations
Jul 2026

STAT3 mediated the isoleucine-induced Alzheimer's disease progression.

Insight is provided into isoleucine as a potential risk factor for AD and STAT3 is identified as a mediator of isoleucine-related AD susceptibility.

Yu Liu, Yuhe Li, Yan-Jun Zhou et al. · 0 citations

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