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Yan Lin

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Aug 2026

Lactylation of EIF4A3 mediates sustained circPTK2 biogenesis to drive prostate cancer metastasis.

Enhanced glycolysis leads to pathological lactate accumulation and promotes malignant tumor progression through protein lactylation. However, the mechanisms by which lactylation enhances RNA processing to drive prostate cancer metastasis remain unclear. Specifically, we found that pathologically accumulated lactate ind...

J. Long, Yan Lin, Yapeng Chen et al. · 0 citations

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