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Author

Yan-Ling Liu

2 papers indexed here

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Open access Nov 2026

Identifying novel genomic alterations in relapsed childhood B-ALL: a report from the Children's Oncology Group.

Relapsed B-acute lymphoblastic leukemia (B-ALL) generally occurs due to the emergence of subclones resistant to therapy, leading to poor outcome. Here, we describe novel genomic alterations responsible for therapeutic resistance at a subtype level in a clinical trial (AALL1331) which randomized patients to blinatumomab...

Yuan Feng, Han-Xia Li, H. Mulder et al. · 0 citations
Open access Oct 2026

Dysregulated AKT signaling reprograms osteosarcoma to drive selective reliance on EP300

It is identified that EP300 controls the growth of AKT-dysregulated osteosarcoma cells by regulating expression of state-specific genetic dependencies by synergizing with EP300 degraders to suppress osteosarcoma growth in vitro and in vivo.

Ian M. Delahunty, S. Nance, Yang Zhang et al. · 0 citations

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