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Aug 2026

Promotion of Angiogenesis with American Ginseng (Panax quinquefolius) After Myocardial Infarction via Targeting DNMT3b-Mediated DNA Methylation and Activating the Notch1/USP5/STAT3 Signaling Axis.

Myocardial infarction (MI) necessitates the promotion of angiogenesis to improve prognosis. Panax quinquefolius saponins (PQS), bioactive constituents of a medicinal and edible homologous plant, are known for their cardiovascular benefits, but their epigenetic mechanisms in post-MI angiogenesis remain unclear. In this...

Jun-Han Yao, Yu Bi, Gang-Tao Bu et al. · 0 citations
Review Open access Sep 2026

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application.

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis. Clinically, RA manifests as joint pain, swelling, and functional impairment caused by persistent synovial inflammation. Additionally, RA can involve vital organs, including the cardiovascular and respiratory systems...

Lu-Xin Li, Jun-Nan Li, Guang-Zhi Li et al. · 0 citations
Review Open access Jul 2026

Pharmacological Effects and Molecular Mechanisms of Lignans in the Treatment of Alzheimer’s Disease

Alzheimer’s disease (AD) is a complex, multifactorial neurodegenerative disorder whose core pathological hallmarks include Aβ aggregation, tau hyperphosphorylation, chronic neuroinflammation, oxidative stress, mitochondrial dysfunction, and gut microbiota dysbiosis. Lignans, a class of naturally occurring polyphenolic...

Li-Meng Sun, Xin-An Zhu, Chunyan Fan et al. · 0 citations

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