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Oct 2026

Enantioselective and Diastereoselective Synthesis of Multisubstituted Spirocyclopentane Oxindoles through NHC Catalysis.

The highly enantio- and diastereoselective N-heterocyclic carbene-catalyzed [3 + 2] annulation of isatin-derived enals and α-EWG-functionalized chalcones is disclosed. Developed herein is an efficient, operationally simple, and general synthetic protocol for the straightforward construction of spirocyclopentane oxindol...

Yan Liu, Wei-Xing Zeng, Shi-Wu Li et al. · 0 citations

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