Author

Yan Niu

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Open access Sep 2026

Nitazoxanide alleviates collagen-induced arthritis by inhibiting STAT3-dependent Th17 cell differentiation and inflammatory cytokines production

Nitazoxanide (NTZ), an FDA-approved anti-parasitic drug, has shown anti-inflammatory effects in rheumatoid arthritis (RA) fibroblast-like synoviocytes, yet its impact on immune cell function and its potential synergy with methotrexate (MTX) remains unclear. In this study, using a murine collagen-induced arthritis (CI...

Chang-Hong Li, Xiao-Li Chen, Yi-Jun Han et al. · Frontiers in Pharmacology · 0 citations

Aug 2026

Dual-cargo polymeric micelles with tumor-cell/stroma dual-targeting for synergistic eradication of drug-resistant breast cancer.

This combinatorial nanomedicine strategy pioneers a paradigm shift in overcoming multidrug resistance by concurrently targeting tumor plasticity and microenvironmental protection, providing a clinically translatable blueprint for treatment-refractory malignancies.

Yunyu Xie, Xin Feng, Zhenyu Wang et al. · Biomaterials Science · 0 citations