Review
Open access
Sep 2026
PIWIL4: from biological characteristics to disease pathogenesis and clinical applications
PIWIL4 is a core component of the PIWI/piRNA pathway. Its roles in germ cell development, transposon silencing, and genome stability maintenance are well established. Recent studies have shown that PIWIL4 is abnormally expressed in many cancers. There, it helps regulate key malignant processes—including cell cycle cont...
Qi Deng, Yi Liu, Yang Qu et al.
· Frontiers in Oncology · 0 citations