CrossScale-GLIO: Topology-Preserving Vision-Language Alignment of MRI and Whole-Slide Histopathology for Diffuse Glioma
CrossScale-GLIO, a visual multimodal framework that represents MRI as a tumor-habitat graph and histology as a cell-niche graph, then aligns them with a structure-aware optimal transport objective anchored by diagnostic language, confirms that preserved relational topology drives cross-scale correspondence.