Open access
Aug 2026
Injury-transduced oligodendrocytes modulate neuroinflammation and glial activation in diseased and non-diseased central nervous system
It is shown that OLs respond to demyelinating diseases by increasing the expression and secretion of serine protease inhibitor clade A member 3N (SERPINA3N), and that SerpinOLs represent a common population of injury-transduced OLs that contributes to CNS pathology beyond myelin production.
Yan Wang, Mei-Na Zhu, Joohyun Park et al.
· Nature Communications · 0 citations