Author

Yan Wang

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Review Open access Sep 2026

Targeting Metabolic Pathways to Direct T-Cell Trafficking: Therapeutic Perspectives

Despite advances in immunomodulatory therapies, dysregulated T-cell trafficking persists as a pathological cornerstone in chronic inflammation, autoimmunity, and cancer. This spatially precise navigation—orchestrated by receptor–ligand cascades—ensures immune surveillance but drives disease when impaired. Targeting ind...

Xiayinan Song, Sheng-Xuan Zhao, Wei-Heng Zhang et al. · Biomedicines · 0 citations

Review Open access Jul 2026

The potential role of aberrant microglial synaptic pruning in the neurodevelopmental pathogenesis of tourette syndrome

A perspective of tourette syndrome is proposed as a microstructural developmental disorder of the circuitry rather than a mere neurotransmitter imbalance, providing a critical theoretical foundation for developing precise, next-generation neuroimmune-modulating interventions.

Lu Lu, Y. Zang, Caiwei Song et al. · Frontiers in Neuroscience · 0 citations