Open access
Jul 2026
Rhein from a traditional herbal formula attenuates hepatic fibrosis via ALDH1A3-mediated retinoic acid metabolism
Rhein is a key antifibrotic constituent of FHG and suppresses hepatic fibrosis by targeting ALDH1A3 and restoring RA metabolism and the ALDH1A3-ATRA axis represents a central mechanism and a promising therapeutic target.
Kai Yu, Minqi Chen, Wanchao Hou et al.
· Chinese Medicine · 1 citation