Ultrasound-activated Piezocatalytic nanomedicine for tumor microenvironment remodeling and immunotherapy.
The physical and immunosuppressive features of the tumor microenvironment limit drug delivery, immune-cell infiltration, and the response of many solid tumors to immunotherapy. Piezocatalytic nanomedicine uses ultrasound to activate piezoelectric nanomaterials, producing charge separation, local electrical effects, and...