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Yan-Xu Xiao

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Open access Aug 2026

Retinoic acid alleviates manganese-induced neurotoxicity in SH-SY5Y cells via the Trim28/α-synuclein/H4K91ac epigenetic axis

Background Manganese (Mn)-induced neurotoxicity is a major public health concern. The aim of this study is to assess whether retinoic acid, a metabolite of vitamin A, can counteract manganese-induced neurotoxicity in SH-SY5Y cells by counteracting epigenetic dysregulation. Methods In vivo, we assessed neurobehavioral f...

Chun-Yan Ao, Hao Liu, Ru-Yun Ban et al. · 0 citations

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