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Author

Yan-Yang Chen

2 papers indexed here

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Aug 2026

Poly(l-glutamic Acid)-Based Microgels with Long-Term Synergistic Lubrication and MMP-Responsive Anti-Inflammatory Delivery for Osteoarthritis Therapy.

Osteoarthritis (OA) is a degenerative joint disease characterized by the failure of cartilage lubrication and persistent inflammation induced by friction-generated debris. Therefore, an effective OA treatment strategy should simultaneously enhance joint long-term lubrication and suppress inflammation. Toward this goal,...

Rong Wu, Yan-Yang Chen, Jun-Yu Wu et al. · 0 citations
Review Open access Sep 2026

Adaptive hydrogel platforms for infected bone defect repair: microenvironmental responsiveness, osteoimmunomodulation, and regenerative remodeling

Infected bone defects remain a major clinical challenge because persistent bacterial colonization and biofilm formation coexist with chronic inflammation, oxidative stress, osteoimmune imbalance, vascular injury, and impaired bone regeneration. Conventional treatment relies primarily on surgical debridement, antimicrob...

Jian-Bo Feng, Huang Kun, Shi-Ping Chen et al. · 0 citations

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