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Author

Yanyong Yang

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2 papers indexed here

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Review Oct 2026

RIPK1 kinase and scaffold activities in tumor cell fate and therapy.

Receptor-interacting protein kinase 1 (RIPK1) plays a pivotal role in regulating cell survival and death, thereby exerting complex and multifaceted functions in the initiation and progression of cancer. Its expression is frequently dysregulated across diverse malignancies and correlates strongly with poor prognosis, hi...

Jing-Yu Luo, Shu-Ya Song, Ze-Kun Li et al. · 0 citations
Aug 2026

Repurposing tirbanibulin as an orally active E2-targeting entry inhibitor against Chikungunya virus.

BACKGROUND AND PURPOSE Chikungunya virus (CHIKV) causes severe acute and chronic disease, yet no approved specific antiviral treatment exists. To rapidly identify potential treatments, we aimed to screen an FDA-approved drug library for inhibitors of CHIKV infection. Tirbanibulin, a dual-microtubule polymerization and...

Jing-Wen Gu, Yan-Hua He, Yu-Qing Ma et al. · 0 citations

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