Open access
Oct 2026
Enzymatic In Situ Self-Assembly of a Fluorogenic Photosensitizer Induces PANoptosis for Photodynamic-Immunotherapy.
PANoptosis, an inflammatory programmed cell death that integrates pyroptosis, apoptosis, and necroptosis, holds great promise for cancer immunotherapy. However, conventional strategies relying on PANoptosome assembly are hindered by complex upstream signaling requirements. Here, we report P-CHD-TPP, an enzyme-instructe...
Yu-Yang Tian, Peng-Ke Zhao, Meng-Xian Ling et al.
· Angewandte Chemie · 0 citations