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Author

Yanan Jiang

2 papers indexed here

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Review Open access Aug 2026

The SF3b complex in cancer: structural basis, molecular mechanisms, and therapeutic opportunities.

The SF3b complex is positioned as a disease-modifying hub at the intersection of RNA splicing and cancer biology, and highlights the opportunities and challenges associated with therapeutically targeting spliceosome components in oncology.

Shulin Li, Li-Tong Shang, Jia-Yi Yang et al. · 0 citations
Aug 2026

Humanized CD70-targeted CAR-T cells with reduced fratricide demonstrate potent antitumor activity against AML and RCC.

A humanized CD70-targeted CAR-T cell therapy is developed, A174-hu1-CAR-T, with reduced fratricide and potent antitumor activity, providing a preclinical foundation to support further translational development.

Meng-Jia Zhang, Zhihao Wang, Cheng Gao et al. · 0 citations

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