Author

Yang Chen

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Open access Aug 2026

CRISPR-Mediated POSTN Editing Modulates Proliferation, Apoptosis, and Molecular Profiles of Primary Rabbit Hair Follicle Stem Cells via the cAMP/PKA/CREB Signaling Pathway

Hair follicle stem cells (HFSCs) are critical for hair follicle (HF) morphogenesis and cyclic hair regeneration. Periostin (POSTN), an extracellular matrix protein involved in tissue development and skin cell regulation, remains poorly characterized in HFSCs. In this study, we constructed CRISPR/Cas9 vectors targeting...

Jia-Wei Cai, Bohao Zhao, Ao-Yun Fan et al. · Cells · 0 citations

Open access Sep 2026

Integrative Analysis of the Metabolome and Transcriptome Reveals the Mechanism Underlying Differences in Skin Development Between the New Zealand Rabbit and the Rex Rabbit

Simple Summary The Rex rabbit is a representative fur-type breed, yet the molecular mechanisms underlying its distinct fur characteristics relative to meat-type rabbit breeds remain incompletely understood. In this study, fur quality traits were evaluated in Rex and New Zealand White rabbits, followed by integrated met...

Bohao Zhao, Jia-Wei Cai, Zi-Yan Bai et al. · Animals · 0 citations

Open access Aug 2026

Vitamin E promotes dermal papilla cell proliferation via the lncRNA2919/STAT1 axis to activate the Hedgehog signaling pathway

Hair-follicle development is a key determinant of the quality and yield of Angora rabbit wool. Vitamin E (VE) has antioxidant properties and regulates cell proliferation. However, the molecular mechanism by which VE regulates hair-follicle growth is unclear. This study investigated the effects of VE on hair follicles a...

Yinuo Fang, Sen Wang, Chengpeng Cao et al. · Non-coding RNA Research · 0 citations